1. Check the batteries in the remote control and replace if necessary.
2. Check the range of the remote control by pointing it at the Smart TV and pressing a button to see if the TV responds.
3. Verify the power is on and the TV is selected as the active device for the remote.
4. Make sure that there are no obstacles between the remote and the TV.
5. Check if the TV is responding to another remote by trying a different remote control.
6. Reset the TV to factory settings and try again.
7. If all else fails, it is time to contact customer service.