Check the following:

1. Make sure you have the necessary permissions to manage rules.
2. Check your Outlook client is up to date.
3. Ensure that the Outlook application is running with Proper permissions.
4. Check if any other rules are conflicting with the one you wish to create.
5. Verify that no user created rules are taking precedence over the ones you are editing.
6. Test the conditions associated with the rules.
7. Confirm that the action tasks associated with the rules still exist.