Follow these steps to troubleshoot Outlook email signature misalignment:

1. Check the email account settings to make sure the signature is properly formatted.

2. Check to see if the signature is set to be linked with only one email address, or with all email addresses.

3. Try to repaire the Outlook installation to resolve any conflicts.

4. Run an in-depth system cleanup to remove any programs that may cause conflicts.

5. Check the HTML code of the signature for any possible errors.