How do I troubleshoot issues with automatic email replies not working in Exchange?

1. Make sure the out of office message is enabled and has a start and end date.
2. Verify that the user has given permission to activate the out of office feature.
3. Make sure that there is no filter other than the Out of Office filter that may be blocking responses.
4. Verify that no rules are configured to loop replies back to the same sender.
5. Check to ensure that the Out of Office feature hasn’t expired.