Here are the steps to remove a co-teacher from a specific assignment on Microsoft Classroom:
Sign into the Microsoft 365 account associated with your Microsoft Classroom.
Open the Classroom you would like to edit and select the class.
Select Assignments from the left navigation.
Select the assignment to open the assignments page.
Select Manage Co-Teachers.
Select the co-teacher you would like to remove from the assignment.
Select the trash can icon next to their name.
The co-teacher will be removed from the assignment.