Here are a few steps you can take to troubleshoot applications not opening:

1. Check the version of the application
   Verify that the version of the application is supported on your computer and is compatible with other applications.
2. Check for updates
   Make sure that you have the latest version of the application. Check the app store or developer website to ensure that application is up to date.
3. Check for potential conflicts
   Review what applications and services are running in the background before opening the application. Disable any services with potential conflicts.
4. Review application specific troubleshooting steps
   Many applications have specific troubleshooting steps that address common issues. Review the makers documentation for troubleshooting resources.