When trying to create a new domain in Active Directory, here are some key points to consider:

1. Ensure that the version of the directory is compatible with the version of the server.
2. Investigate the state of any existing domains and determine if changes need to be made.
3. Familiarize yourself with the requirements for DNS roles and services.
4. Make sure you have an available domain controller and the resources necessary to maintain one.
5. Understand and apply best practices for the database and server configuration.
6. Verify that the new domain works properly with profiles, group policies, and security.